Research Projects

The four guiding missions of our lab are:

1. Through modeling and experiment, to understand the physiological processes that give rise to neocortical memory, learning, and cognition.
2. To understand the pathophysiology underlying cortical dementia and abnormal cognition.
3. To use such knowledge to create brain-like artificial intelligence and neural prosthetic devices.
4. To develop computational innovations that facilitate the goals above.

Active research projects:

* (Computer Engineering) Implementation of a biologically realistic yet scalable and efficient brain simulator.
* (Web Interface) Secure yet full-featured design, execution, monitoring, and analysis of neuronal models for collaborating investigators via remote WWW access.
* (Neural Modeling) Translation of laboratory findings into accurate neuronal parameters, especially dynamics of synapses, channels, calcium, kinase & phosphorlyase, and nucleic acid expression systems.
* (Multisensory Integration) Modeling of auditory, visual, and tactile perception with emphasis on associational representation and robotic applications.
* (Disease Modeling) Modeling of Alzheimer-type dementia, with emphasis on synaptic and channelopathies that might be targeted through intelligent drug design and molecular biology.
NeoCortical Simulator .v3
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